ANDROPAUSE: ENDOCRINOLOGY, ERECTILE DYSFUNCTION, AND PROSTATE PATHOPHYSIOLOGY

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Pathophysiology and treatment of diabetic erectile dysfunction.

The pathophysiology of diabetes is multifactorial and no single etiology is at the forefront. The proposed mechanisms of erectile dysfunction (ED) in diabetic patients includes elevated advanced glycation end-products (AGEs) and increased levels of oxygen free radicals, impaired nitric oxide (NO) synthesis, increased endothelin B receptor binding sites and ultrastructural changes, upregulated R...

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Radical prostatectomy (RP) is the gold standard treatment for localized prostate cancer; yet erectile dysfunction (ED) in selected series is still reported as high as 80% after this surgery. Patient selection and surgical technique (i.e., preservation of neurovascular bundles) are the major determinants of postoperative ED. Pharmacological treatment of postoperative ED, using either oral or loc...

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Role of Oxidative Stress in Pathophysiology of Erectile Dysfunction

16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 Erectile dysfunction (ED) is a highly prevalent and often underestimated problem in the general population. Systemic risk factors such as diabetes, hypertension and hyperlipidemia increase the incidence of erectile dysfunction. The pathophysiology of ED is multifactorial, and endothelial dysfunction appears to play a key role. Nitric oxide r...

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Prostate cancer: 8. Urinary incontinence and erectile dysfunction.

The case A 68-year-old sexually active man is referred to a urologist for consideration of radical prostatectomy following diagnosis of prostate cancer. Rectal examination has revealed a single nodule confined to the prostate, and the Gleason score is 6. The patient has talked to friends and has done some reading and is very concerned about the possibility of urinary incontinence and erectile d...

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Erectile dysfunction and the risk of prostate cancer

BACKGROUND Prostate cancer (PCa) is the most commonly diagnosed malignancy and the third leading cause of cancer death among men in developed countries. Because some risk factors are common between erectile dysfunction (ED) and PCa, we investigated the association between ED and subsequent PCa. METHODS This nationwide population-based cohort study used data from the Taiwan National Health Ins...

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ژورنال

عنوان ژورنال: Archives of Andrology

سال: 2004

ISSN: 0148-5016

DOI: 10.1080/01485010490274131